Key Functions of NMN:

• NAD+ Biosynthesis: One of the primary functions of β-NMN is as a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme found in all living cells. NAD+ is essential for various metabolic reactions, including those involved in energy production, DNA repair, and gene expression regulation. β-NMN is converted into NAD+ via the enzyme nicotinamide phosphoribosyltransferase (Nampt) pathway.
• Energy Metabolism: NAD+ is a critical component in cellular energy production processes, such as glycolysis, the tricarboxylic acid (TCA) cycle, and oxidative phosphorylation. By serving as a precursor to NAD+, β-NMN indirectly supports these energy-producing pathways.
• Sirtuin Activation: NAD+ is a co-substrate for sirtuins, a family of proteins that regulate various cellular functions, including DNA repair, inflammation, and metabolism. By increasing cellular NAD+ levels, β-NMN can indirectly activate sirtuins, promoting their beneficial effects on cellular health and longevity.
• Aging Regulation: β-NMN has garnered significant interest for its potential role in slowing down the aging process. As NAD+ levels decline with age, supplementation with β-NMN may help maintain cellular NAD+ levels, thereby supporting cellular functions associated with youthfulness and potentially extending lifespan.
• DNA Repair: NAD+ is required for several enzymes involved in DNA repair processes, including poly(ADP-ribose) polymerases (PARPs). By promoting NAD+ synthesis, β-NMN may contribute to the maintenance of genomic integrity and the repair of DNA damage.