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Chemical Name
CAS
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nicotinamide adenine dinucleotide phosphate
| Cas No. | 53-59-8 |
| Molecular Formula | C21H28N7O17P3 |
| Purity. | ≥98% |
| Molecular Weight | 743.41g/mol |
Properties
| Chemical Name | nicotinamide adenine dinucleotide phosphate |
| Synonyms |
NADP+ |
| CAS No. | 53-59-8 |
| Molecular Formula | C21H28N7O17P3 |
| Molecular Weight | 743.41g/mol |
| Appearance | |
| Storage and Shipping Conditions | |
| Industries | β-nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-nicotinamide adenine dinucleotide 2′-phosphate reduction (NADPH) form a coenzyme redox pair (NADP+:NADPH), which participates in a wide range of Enzymes catalyze redox reactions. |
| Applications | |
| Description | NADP+ (Nicotinamide Adenine Dinucleotide Phosphate) is a coenzyme that plays a crucial role in cellular metabolism, particularly in the processes of oxidation-reduction (redox) reactions. It is closely related to NAD+ (Nicotinamide Adenine Dinucleotide), with the main difference being the additional phosphate group on the 2' position of the ribose ring in NADP+. While NAD+ is involved primarily in energy production through catabolic reactions (such as glycolysis and the citric acid cycle), NADP+ is more involved in anabolic reactions, which are processes that build molecules and store energy. |
Key benefits of NADP+:
- Redox Reactions: Like NAD+, NADP+ is involved in redox reactions, where it alternates between its oxidized form (NADP+) and its reduced form (NADPH). These reactions are critical for maintaining cellular homeostasis and energy balance.
- Antioxidant Defense: NADPH, the reduced form of NADP+, is essential for the activity of antioxidant enzymes like glutathione reductase and thioredoxin reductase, which protect cells from oxidative damage. NADPH helps regenerate antioxidants (like reduced glutathione) that neutralize free radicals and prevent cellular damage.
- Photosynthesis (in Plants): In plants, NADP+ is involved in photosynthesis, where it plays a key role in the light-dependent reactions. During these reactions, NADP+ is reduced to NADPH, which is then used in the Calvin cycle to help synthesize glucose from carbon dioxide and water.
- Immune System Support: NADPH is critical for the function of immune cells like neutrophils and macrophages, helping them produce reactive oxygen species (ROS) to destroy pathogens during the immune response. It also supports the activity of certain enzymes involved in immune cell signaling.