In July 2017, the European Union (EU) issued Regulation 2017/1281 on ergothioneine, approving it as a new resource food ingredient, and listing the specifications, heavy metal content, microbial standards, usage limits, etc. of ergothioneine added to food wait.

Heavy metal limits in ergothioneine

In November 2017, the European Food Safety Authority (EFSA) issued a report on the safety assessment of synthetic L-ergothioneine as a new resource food for infants, pregnant women and lactating women. Under the recommended use and level of use, it is safe to use as a new resource food in the diet of infants, pregnant women and lactating women.

Maximum daily intake of ergothioneine based on aggregate toxicological data

In August 2019, the U.S. Food and Drug Administration (FDA) designated ergothioneine generally recognized as safe (GRAS) under "intended conditions of use," a decision that allows product manufacturers to add this powerful antioxidant to various Among the best-selling consumer products are cosmetics, beauty products, food, beverages and health products.

Ergothioneine food additive limit

In addition to protecting cells and tissues from oxidative damage, ergothioneine has also been proven to have a protective effect on nerves and can inhibit memory impairment. Japan's "Kaiyuan Pharmaceutical Co., Ltd. (KAIGEN)" has launched a drug for the improvement of middle-aged and elderly people. Ergothioneine dietary supplement products for memory loss.

KAIGEN Ergothioneine Supplements

In addition, the well-known American dietary supplement brand "Super Smart" and the Canadian organic mushroom health food brand "Real Mushrooms" have launched dietary supplements with ergothionein as the main ingredient, claiming that they can effectively help human cells and tissues resist Oxidation, anti-inflammation, inhibition of heavy metal toxicity, protection of the brain from neurotoxins, prevention of cognitive decline, promotion of cellular respiration and lipolysis, enhancement of physical fitness and endurance performance during exercise, etc.

Super Smart Ergothioneine Dietary Supplement

Real Mushrooms Ergothioneine Dietary Supplement

In addition to skin care products and food additives, ergothioneine is also widely used in the treatment of organ transplantation, cell preservation, eye surgery, etc., because of its deep-penetrating mitochondrial mitochondria and direct access to the "focus" antioxidant function. major.