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(S)-1-(3-Bromopyridin-2-yl)ethan-1-ol

Cas No. 317845-81-1
Molecular Formula
C7H8BrNO
Purity. ≥99%
Molecular Weight 202.05 g/mol
Properties
Chemical Name (S)-1-(3-Bromopyridin-2-yl)ethan-1-ol
Synonyms
317845-81-1;(1S)-1-(3-bromo-2-pyridyl)ethanol; (S)-1-(3-Bromopyridin-2-yl)ethan-1-ol;(S)-1-(3-Bromopyridin-2-yl)ethanol;(1S)-1-(3-bromopyridin-2-yl)ethanol;(1S)-1-(3-bromopyridin-2-yl)ethan-1-ol; (S)-1-(3-Bromo-2-pyridyl)ethanol
CAS No. 317845-81-1
Molecular Formula C7H8BrNO
Molecular Weight 202.05 g/mol
Appearance White Powder
Storage and Shipping Conditions
Industries Pharmaceutical intermediates
Applications
1. Pharmaceutical Field (Core Applications) a. Pharmaceutical Intermediate: Used in the synthesis of pyridine-based targeted drugs, including antitumor agents (e.g., EGFR inhibitors), antibacterial drugs, and antiviral drugs. Its chiral structure and pyridine ring enhance the specificity of drug-target binding. b. Drug Molecular Modification: Through derivatization reactions involving hydroxyl and bromine groups, it optimizes drug solubility, lipophilicity, and metabolic stability, thereby improving efficacy and reducing side effects. c. Peptide and Small-Molecule Drug Construction: Serves as a chiral building block in the synthesis of heterocyclic peptide mimetics and alkaloid drugs, enriching the structural diversity of drug molecules. 2. Fine Chemical Industry a. Chiral Synthesis Reagent: Functions as a chiral source in asymmetric synthesis for producing optically pure intermediates for dyes and fragrances. Its chiral hydroxyl group enables directional introduction into target molecules. b. Organic Functional Material Precursor: Utilizes the coordination of pyridine rings with metal ions to prepare chiral catalysts and optically active polymer materials, meeting the needs for specialized functional materials.