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Histamine dihydrochloride

Cas No. 56-92-8
Molecular Formula
C5H11CI2N3
Purity. ≥99%
Molecular Weight 184.07g/mol
Properties
Chemical Name Histamine dihydrochloride
Synonyms
TIMTEC-BBSBB003722;2-[4-IMIDAZOYL]-ETHYLAMINEDIHYDROCHLORIDE;2-(1H-IMIDAZOL-4-YL)-ETHYLAMINE2HCL;2-(1H-IMIDAZOL-4-YL)ETHYLAMChemicalbookINEDIHYDROCHLORIDE;1H-IMIDAZOLE-4-ETHANAMINEDIHYDROCHLORIDE;2-imidazol-4-ylethylaminedihydrochloride;HISTAMINEDICHLORHYDRATE
CAS No. 56-92-8
Molecular Formula C5H11CI2N3
Molecular Weight 184.07g/mol
Appearance White Powder
Storage and Shipping Conditions
Industries Pharmaceutical intermediates
Applications
1. Pharmaceutical Raw Materials: Used as reference standards or intermediates in the synthesis of antihistamines, aiding in the development of drugs for treating allergies, urticaria, and other conditions. 2. Topical Medication Ingredients: Low-concentration preparations can be used to alleviate symptoms such as skin itching and eczema by reducing inflammatory responses through local action. 3. Emergency Care Applications: Serve as tool compounds in drug research and development for studying the pathogenesis of anaphylactic shock and evaluating the efficacy of emergency medications.
Description Histamine dihydrochloride (trade name Ceplene) is a salt of histamine that is used as a drug for the prevention of relapse in patients diagnosed with acute myeloid leukemia (AML). It is also an FDA-approved[1] active ingredient for topical analgesic use for the temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, bruises, sprains, and strains and is available in over-the-counter (OTC) products.