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L(-)-Pipecolinic acid

Cas No. 3105-95-1
Molecular Formula
C6H11NO2
Purity. ≥99%
Molecular Weight 129.16 g/mol
Properties
Chemical Name L(-)-Pipecolinic acid
Synonyms
l-Pipecolic acid; (S)-Piperidine-2-carboxylic acid; L-Homoproline; (2S)-piperidine-2-carboxylic acid; L-Pipecolinic acid
CAS No. 3105-95-1
Molecular Formula C6H11NO2
Molecular Weight 129.16 g/mol
Appearance White Powder
Storage and Shipping Conditions
Industries Pharmaceutical intermediates
Applications
1. Pharmaceutical Field (Core Applications) a. Pharmaceutical Intermediates: Used in the synthesis of anti-HIV drugs, antidepressants, antibacterial agents, and more, serving as key building blocks for chiral drug molecules. b. Drug Optimization Raw Materials: Utilized to modify drug molecules through their chiral structures, enhancing the bioactivity, selectivity, and metabolic safety of drugs. c. Peptide Drug Synthesis: Acts as a component of polypeptide chains, employed in the preparation of peptide drugs with specific physiological functions (e.g., antimicrobial peptides, regulatory peptides). 2. Fine Chemical Industry a. Chiral Catalyst Ligands: Can coordinate with metal ions to prepare chiral catalysts, used in asymmetric synthesis reactions (e.g., hydrogenation, cycloaddition reactions). b. Organic Synthesis Intermediates: Applied in the synthesis of dyes, fragrances, food additives, etc., with their cyclic structures imparting special properties to the products. 3. Materials Science Field a. Polymer Material Monomers: Used in the preparation of functional polymer materials (e.g., polyamides, polyurethanes), enhancing the mechanical strength and biocompatibility of the materials. b. Biomaterial Modifiers: Employed to modify biomedical materials (e.g., artificial cartilage, tissue engineering scaffolds), improving their cell compatibility and degradation properties.
Description L-pipecolic acid is the L-enantiomer of pipecolic acid. It is a metabolite of lysine. It has a role as a plant metabolite and a human metabolite. It is a conjugate acid of a L-pipecolate. It is an enantiomer of a D-pipecolic acid. It is a tautomer of a L-pipecolic acid zwitterion.