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N-Acetyl-D-mannosamine

Cas No. 7772-94-3
Molecular Formula
C8H15NO6
Purity. ≥99%
Molecular Weight 221.21 g/mol
Properties
Chemical Name N-Acetyl-D-mannosamine
Synonyms
N-acetyl-D-mannosamine; ManNAc; n-acetyl-mannosamine 2-Acetamido-2-deoxy-D-mannopyranose; 2-Acetamido-2-Deoxy-Mannose; 2-Deoxy-2-Acetamido-Mannose;2-Deoxy-2-Acetamido-D-Mannose; 2-Acetamido-2-Deoxy-Mannopyranose; 2-Deoxy-2-Acetamido-Mannopyranose
CAS No. 7772-94-3
Molecular Formula C8H15NO6
Molecular Weight 221.21 g/mol
Appearance White Powder
Storage and Shipping Conditions
Industries New food raw materials, cosmetic raw materials, pharmaceutical intermediates
Applications
1. Biopharmaceuticals (Core Applications) a. Drug Raw Materials: Serves as a direct precursor for synthesizing sialic acid (N-acetylneuraminic acid), used in the preparation of intermediates for anti-influenza and anti-inflammatory drugs. b. Rare Disease Treatment: Applied in the development of drugs for treating mucopolysaccharidosis type IIIB (Sanfilippo B syndrome) by supplementing key metabolites deficient in patients, thereby slowing disease progression. c. Immunomodulation and Antiviral Applications: Research indicates it can enhance immune cell activity, aiding in the development of antiviral agents (e.g., drugs targeting respiratory viruses and herpes viruses). d. Cell Signaling Research: Functions as a tool molecule for exploring the effects of glycosylation modifications on cell signaling and tumor metastasis, supporting targeted drug development. 2. Food and Health Supplements a. Functional Nutritional Fortifier: Added to infant formula and health products for middle-aged and elderly individuals to promote endogenous sialic acid synthesis, supporting brain development and immune enhancement. b. Anti-Aging Health Product Ingredient: Marketed for "improving cellular glycosylation and delaying aging," formulated into oral solutions, chewable tablets, and other products tailored for anti-aging consumers. c. Gut Health Products: Serves as an auxiliary ingredient in gut health supplements by regulating gut microbiota balance and promoting intestinal mucosal barrier repair. 3. Cosmetics a. Anti-Aging and Repair Ingredient: Promotes the synthesis of skin cell surface glycoproteins, enhances skin barrier function, reduces fine lines and dryness, and is incorporated into creams and serums. b. Moisturizing and Anti-Inflammatory Properties: Exhibits excellent water solubility and moisturizing capacity while soothing skin inflammation, making it suitable for anti-aging and repair products for sensitive skin. c. Hair Care Component: Modifies the glycosylation structure of hair keratin, improving hair smoothness and strength, and is used in high-end shampoos and hair care oils.
Description N-acetyl-D-mannosamine is an N-acetylmannosamine having D-configuration. It has a role as a bacterial metabolite. It is a N-acyl-D-mannosamine, a N-acetyl-D-hexosamine and a N-acetylmannosamine.